Quick Answer: Is Cystic Fibrosis A Chromosomal Disorder?

What type of genetic disorder is cystic fibrosis?

Cystic fibrosis is an example of a recessive disease.

That means a person must have a mutation in both copies of the CFTR gene to have CF..

What chromosome causes cystic fibrosis?

The seventh pair of chromosomes has a gene called the CFTR (cystic fibrosis transmembrane regulator) gene. Changes (mutations) or errors in this gene are what cause CF. This gene is very large and complex.

Is Cystic Fibrosis a single gene disorder?

A person must inherit two copies of the CFTR gene that contain mutations — one copy from each parent — to have cystic fibrosis. Some genetic diseases, such as cystic fibrosis, are caused by mutations in a single gene.

What type of mutation occurs in cystic fibrosis?

The most common CF mutation, F508del, is primarily considered to be a processing mutation. The F508del mutation removes a single amino acid from the CFTR protein. Without this building block, the CFTR protein cannot stay in the correct 3-D shape.

What gender is cystic fibrosis most common in?

Cystic fibrosis affects both males and females; approximately 30,000 people in the United States have been diagnosed with the condition.

What are four symptoms of cystic fibrosis?

People with CF can have a variety of symptoms, including:Very salty-tasting skin.Persistent coughing, at times with phlegm.Frequent lung infections including pneumonia or bronchitis.Wheezing or shortness of breath.Poor growth or weight gain in spite of a good appetite.More items…