Why does chicken pox virus reactivate?
After primary infection which results in varicella, the virus becomes latent in the cerebral or posterior root ganglia.
Some of these individuals develop shingles after several decades because of virus reactivation.
It is caused by decline of cellular immune response..
What type of virus is chicken pox?
Chickenpox is a highly contagious illness caused by the varicella-zoster virus (VZV), a type of herpes virus. It is often a mild illness, characterized by an itchy rash on the face, scalp and trunk with pink spots and tiny fluid-filled blisters that dry and become scabs four to five days later.
Is varicella a virus?
Varicella (chickenpox) is an acute infectious disease. It is caused by varicella-zoster virus (VZV), which is a DNA virus that is a member of the herpesvirus group. After the primary infection, VZV stays in the body (in the sensory nerve ganglia) as a latent infection.
Where does the varicella virus lay dormant?
After the primary infection (chickenpox), the virus lies dormant in the nerves, including the cranial nerve ganglia, dorsal root ganglia, and autonomic ganglia. Many years after the person has recovered from chickenpox, VZV can reactivate to cause neurological conditions.
Where does the chickenpox virus become latent?
After a primary infection of chickenpox (varicella) (usually in childhood), VZV establishes a latent infection in the trigeminal and dorsal root ganglia (1, 2). After a variable latent interval the virus reactivates to produce shingles (herpes zoster).
Does chicken pox stay dormant?
It is rare to have chickenpox more than once, as infection gives life-long immunity. Once you have had chickenpox the virus lies dormant (inactive) in the nerves of the spinal cord and can reactivate later in life, this is known as shingles. You cannot catch shingles from another person.